I'd replace them and here's some reasons why.
The next owner of that bike will be happy you did. The bike will be more desirable to buy and easier to sell.
If I was buying a Commando, I'd steer away from a bike with 50K miles on original main bearings. It's good for your Norton parts seller. He needs the business. There HAS to be some wear on those bearings with that kind of mileage, despite what you think the condition might appear appear to be. It all depends on how carefully the previous owners checked/changed the oil, and how it was stored.
We are just temporary stewards of these bikes. It's nice to make them better while they're in your garage.
If you've already removed the engine and split the cases you've done most of the hard work. Seems a shame to quit so close to the finish line. Besides, it's satisfying (fun) work, and It's a good opportunity to check other components inside the crankcase like the big ends, cam bushings, etc. You never know what you'll find inside unless you open her up.
Whenever I buy some old crock, I like to get inside the engine and lay my hands on the innards and make improvements where I can.
This process really makes the bike "mine" in my tiny brain.
I've got the original roller+ball main bearings from my 63 Atlas sitting on my work bench (24K miles) and I can't bear to discard them.
I installed Superblends of course.