I have an 850 with 23T. Some thoughts:
It is probably too highly geared for best performance, but I love its torquey feel, understated performance (always goes faster than it feels) and low revving comfort. At 70mph it's at 3600rpm indicated. I always get off after a ride, impressed with the bikes easy grunt.
This set up wouldn't work if your isolastics are set to allow vibration below 3,000rpm - Since I retorqued the engine mounts, it's vibration is minimal above 2,000rpm and really sweet >2500 and the handling still feels predictable and solid. Taking it easy, I change to 2nd around 25mph, 3rd at 40 and 4th at 50. Over 5500rpm in 2nd is court appearance territory on the country lanes around here.
I guess it all depends on riding style (I like how the bike feels between 2500 and 4500rpm) and how the bike's set up. Also, I have a modern Japanese 4cyl, which gives me my higher revs fix. When the time comes, I'll try a 22T as it might be the best compromise, for me and where I most regularly ride.