I use two 34mm Mk2 Amals with No 6 Mikuni needles with methanol. If I was running petrol, I'd still run a bit rich on the main jets, and adjust the needle to the leanest right across the range from 1/4 to 3/4 throttle until I just stopped getting a miss. For high altitude, I'd lift the needles one notch if they tended to lean off enough to get a miss during gear changes. With conventional Amal needles, it must be almost impossible to get the mixture right from 1/4 to 3/4 throttle ? What I am talking about is really good acceleration up through the gears with no missing or bogging down as you wind the throttle on. I think running slightly rich on the mains is essential in any situation.
That attachment in Steve's photo is similar to the power jet which was fitted to two strokes in the 70s - it richens the mixture at very high gas flows. With two strokes you can achieve similar by recessing the top of the needle jet and metering lower, so at full throttle the motor actually runs on the main jet when the tip of the needle is in the recess. In other words the tip of the needle must always be trapped in case you get a hung throttle.