I wonder if anyone ever remembers the concept of Brake Mean Effective Pressure when developing race classes for various bikes ? When four stroke motors of similar capacity have more valves, the BMEP is higher, and it is also higher in two stroke motors .
Sure, for modern racing classes this is fine, but it does not work when you mix modern bikes with old bikes because it does not take into account the much greater reliability that new engine designs have.
This is also why vintage racing is destroyed when people race replicas in it that have much stronger engine parts than the originals, it instantly makes real vintage bikes obsolete because they can not operate at the same power per cubic inch as the replicas without breaking down.
In AMA racing in the 50s they had the 750cc side-valve Harley and Indian twins running against 500cc OHV bikes. Someone decided that was fair, and it seemed to work out pretty well with both engine configurations taking turns winning races over twenty or so years it was enforced, and everyone seemed to have the same reliability.
In about 1968 Yvonne DuHamel ran a 250 Yamaha on a mile dirt track race in California and was as fast as the 750 Harleys and 500 Trumpets and BSA Goldstars, he finished the race with a very high placing. Maybe if the AMA would have limited 2-strokes to 250cc when it included it in that formula time would have stopped for a while longer for the Harleys and Brit bikes, but they went to 750cc across the board for all engines, so first the side-valves disappeared, then when the Japanese built 350-750cc 2-strokes, all the old bikes were obsolete of course.
No one kept up with Japanese manufacturing so the only bike that survived was the Harley xr750, and then only because the AMA simply outlawed and crippled all it's competition.