A simple compression test with a readily available gauge will be diagnostic enough if the results show a difference that exceeds 10%.
I pulled the carbs of and cleaned again and made sure they were balanced, changed the spark plugs and started the bike without the air filter on. If I put my hand over the the right carbs intake there is a lot of suction there and that cylinder runs better if I put my hand over the left intake there is no where near as much suction and that cylinder starts to cut out
If the carbs are out of sync the results you note would be the same. Simple sync: back the slide height (speed screws) adjusters out such that both slides are sitting on the bottom of the carb body bores, insure that each cable has a tad of slack. Operate the twist grip with high frequency and low amplitude, just hitting the end of the free play is fine, adjust the carb cables such that both slides are getting an impulse at the same time. When you arrive at this point, and feel confident, then use a single 1/4" drill bit as a feeler gauge and raise both slides to give the same feel when the drill bit is placed between the apex of the slides cutaway and the center of the carb's bore. Set the air screws at 1. 1/2 turns out from seat and start the engine. When warmed the idle will be high; uniformly lower the slides to achieve an idle RPM between 900 and 1100. If you need to adjust the air screws (likely) you will need to readjust the slide height, the goal is to have a smooth take-off from rest and a smooth transition to the needle. Once this has been established try your home brew vacuum test again. If you end up with the same results read on.
Cam ware can be easily checked by:
1) Seeing if all lash adjusters are, roughly, showing the same number of threads above the jam nuts.
2) Measuring (observing) the maximum distance the valves are opened; this doesn't have to be done to aero-space specs.
If your cam is worn to a performance degrading level the suggestions above will tell the tale.
If no cam ware is discernible, compression test is good, carbs synced, head torque is verified, ignition timing is correct, then I wager a guess that the Amals, if more than 5 years old, are ready to be put out to pasture. You can clean Amals until they are ready to be surgically implanted in living tissue, but their design and metallurgy are so poor that they are way below the term "planned obsolescence". I'm NOT saying that new Amals don't work well, they just don't last, the latest iteration, the Premiers, would seem to have addressed the prior generation of Concentric's shot comings...
Best.