In a recent magazine article here in the UK, it discussed this issue, but without a definative conclusion

What it did say though, is that Steve Maney, the well known Norton performance parts manufacturer apparently uses the polymide caged bearings in his racers, but the article does go on to say that obviously these engines don't do the milage of a road bike and regularly get stripped down etc.
I have had polymide caged mains in my Norton which are fine, but having said that, I have only done about 3,000 miles since I bought this bike and don't know their history prior to my ownership
Would the worst case scenario be that they need replacing sooner than brass caged or could they disintegrate and cause significant damage to the engine? Apparently (according to the article if I recall correctly) the polymide caged bearings do not have any information suggesting that they are not for use in an internal combustion engine.
I await the more learned amongst us to give a more definative informed opinion.